Nature Chemical Biology

Nature Chemical Biology is an interdisciplinary journal that publishes the most innovative and important research advances at the interface of chemistry and biology. The journal publishes research from chemists who are applying the principles, language and tools of chemistry to biological systems and from biologists who are interested in understanding biological processes at the molecular level. The scope of the journal covers all areas of contemporary research at the interface of chemistry and biology.

Structures of human telomerase with BIBR1532 reveal novel mechanism of inhibition

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Together for RNA breakthroughs

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Druggability is not static

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Challenges and opportunities in RNA-centered therapeutics

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Generation of membrane-permeable cyclic peptides inhibiting protein–protein interaction

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Rapid H₂O₂-free, radical-and oxygen-driven proximity labeling in living cells and in vivo

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A potent alternative cysteine production pathway allows reductase independence

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Piercing myeloma’s Achilles’ heel

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