Nature Methods

Nature Methods offers a unique interdisciplinary forum for the publication of novel methods. Nature Methods focuses on the life sciences, combining practical, technique-driven subject matter with rigorous peer-review standards to ensure that readers are consistently presented with only the most valuable and highest quality methodological research. The journal offers its readers primary research papers as well as an array of opinions, reviews and short journalistic pieces to provide busy researchers with a broad, yet easily absorbed perspective of important methodological developments in the life sciences.

Reading and writing neural activity with Neuropixels Opto probes

---

Neuropixels Opto: combining high-resolution electrophysiology and optogenetics

---

iPS cells: history made and history in the making

---

TADShop: systematic benchmarking and identification of topologically associating domains

---

External validation improves generalizability, replicability and reproducibility in predictive models for neuroimaging

---

Adding chemical identity to cryo-electron microscopy

---

LGBTQ+ allies to count on

---

Teaching an old dog new cells

---