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Conformational changes in proteins are vital to their function yet remain challenging for state-of-the-art artificial intelligence, such as AlphaFold3, to predict. Researchers at the Institute for Molecular Science (IMS), and the Graduate University for Advanced Studies, SOKENDAI introduced a repulsive force between predicted structures, allowing AlphaFold3 to sample the multiple conformational states that its default settings rarely capture.

A study led by the University of Jyväskylä in Finland evaluated, for the first time, an ecological threshold for the amount of clearcutting in boreal forests. According to the results, maintaining populations of bird species specialized in old-growth forests requires either a forest rotation period of at least 90 years on average or that approximately one-fifth of the forest area be excluded from clearcut management. The study provides a concrete target for the ecologically sustainable use of forests.

Astronomers have found two clouds of hydrogen near the Whirlpool galaxy that appear to contain almost no stars. The clouds, discovered with China's FAST radio telescope, each contain roughly 3 million times the mass of the sun in hydrogen but have no detectable optical counterpart. Their properties are outlined in a new paper published in the Astronomy & Astrophysics journal on Aug. 4.

The human-animal bond is often so strong that pet owners may delay or forgo medical treatment or leave a health care facility against medical advice if they have no one to care for their pet at home. A perspective paper published in the New England Journal of Medicine explains why pet owners may need different approaches to care when hospitalized, according to an Emory University physician and an Ohio State University veterinarian.

Here's a novel idea for countering the painful side effects of chemotherapy: Beforehand, take the hallucinogenic drug found in magic mushrooms.

In 1974, Stephen Hawking made a prediction that transformed our understanding of black holes. Black holes, he showed, are not truly black: They slowly lose energy through a quantum process now known as Hawking radiation. The lighter the black hole, the faster it evaporates.

New research has found that tree species diversity can play a crucial role in protecting forests from the growing threat of extreme climate events. The study analyzed data from 88,116 separate forest plots across the United States to investigate the impact of "compound climate extremes," when events such as drought and extreme heat occur at the same time.

Narwhals have nature's only straight tusk, a single tooth up to three meters (10 feet) long, so strange they were sold as magical unicorn horns during the Middle Ages.

When humans are making decisions, they are known not to rely solely on their own considerations and the evidence available to them. Past behavioral science and psychology studies have shown that people are often also influenced by the choices and opinions of others.

Lakes may look like picturesque stopping points along a river or stream, but they can have a big influence on what happens to carbon as it moves through a landscape. New research suggests that the more lake-rich a network of streams is, the more carbon is released into the atmosphere rather than carried downstream.

Has El Niño reached the West Coast? You might think it has. After all, the ocean off Southern and Central California is unusually warm. But that warmth is from a recent marine heat wave that predates the current El Niño. Much of the Pacific Coast is experiencing relatively normal conditions while still awaiting the impacts of what could be a very strong El Niño.

A study on Roman law by the Carlos III University of Madrid analyzes the regulations and complex imperial logistics governing the capture, transport and safety of animals used in spectacles in the Roman Empire—which were far more popular than gladiatorial combat.

UC Riverside scientists have developed a way to identify where Earth's biggest earthquakes are most likely to occur, offering a powerful new tool for improving disaster preparation in some of the most dangerous seismic regions.

Thick smog has blanketed parts of Indonesia as the vast archipelago battles fires that have burned large swaths of Borneo and Sumatra for weeks.

An orangutan mother and her baby, threatened by wildfires encroaching on their habitat in Indonesia, were rescued earlier this week, authorities said in a statement Saturday.

After an eight-year journey, a spacecraft carrying European and Japanese probes began the monthslong, high-risk approach to Mercury on Thursday to study the sun-scorched planet.

Rice University researchers have used a magnetically levitated particle to search for ultraheavy dark matter, extending the hunt for some of the heaviest possible forms of the invisible matter thought to hold galaxies together. Led by Christopher Tunnell, associate professor of physics and astronomy, the researchers used a tiny floating magnet as a highly sensitive detector designed to register the faint push an ultraheavy dark matter particle could produce as it passed through.

Generative artificial intelligence (Gen-AI) has become a routine part of working life, but overreliance on the technology may erode managers' ability to build moral insights, contextual understanding and know-how to get a job done, according to a new study from the University of Bath.

School suspensions are associated with a complex combination of socioeconomic disadvantage, special educational needs, peer relationships and students' experiences of school, according to new research from The University of Manchester.

The catastrophic flooding in July 2021 claimed the lives of more than 200 people in Germany and Belgium. The high death toll makes it clear that hazard mapping and risk communication must be improved urgently. Researchers at the University of Potsdam, the Helmholtz Centre for Geosciences, the University of Louvain and Johns Hopkins University analyzed the locations and specific circumstances of 224 deaths. Their findings show that many occurred outside the officially mapped flood hazard zones and that older people were particularly affected. The work is published in the journal Earth's Future.

Beneath the Arctic Ocean is an orchestra featuring natural and human composers, from cracking sea ice and whistling beluga whales to humming shipping-vessel engines. Researchers from MIT Lincoln Laboratory heard some of this cacophony when analyzing data from commercial off-the-shelf sensors that they integrated and deployed in 2024 during the U.S. Navy's Operation Ice Camp (OIC). This past March, during OIC 2026, the researchers returned to the Arctic with a higher-fidelity version of one of the sensors, a geophone that detects vibrations in the sea ice.

Researchers at Lund University have developed a new type of light-emitting diode based on thin, branched nanowires that could offer significantly higher efficiency and lower production costs than current technology. By controlling where in the structure the light is generated, the researchers have reduced the losses that would otherwise limit the amount of light that can be used. Their study is published in the journal Nano Research.

Why do some ants help nestmates in distress while others don't? A research team from Johannes Gutenberg University Mainz (JGU) and Tel Aviv University addressed this question in a new study. The researchers examined worker ants of the species Cataglyphis niger, some of which had shown rescue behavior while others had not. The results, recently published in the Journal of Experimental Biology, suggest that the key difference lies not in body size, morphology or the animals' energy reserves, but in gene activity in the nervous system.

Researchers have completely suppressed superconductivity in magic-angle graphene by screening interactions between electrons, helping resolve a long-running debate about the origin of the phenomenon.

The human body and its gut microbiome produce thousands of small molecules that shape how the body functions—influencing immunity, metabolism and more. Identifying what those molecules actually are has been one of the biomedical sciences' most persistent bottlenecks. More than 80% of compounds detected in a typical biological sample cannot be matched to any known structure using current methods.

In a paper published in the journal Marine Pollution Bulletin, researchers at Kyushu University report on what happens when wharf roaches, a common shoreline scavenger, eat expanded polystyrene (EPS). Roaches that fed on EPS showed no significant reduction in lifespan, but their guts displayed altered expression of genes involved in chemical defense, DNA repair and digestion. Analysis of the wharf roach gut microbiome showed little change, but several rare microbes were found only in the EPS-fed specimens.

A study of preschool children found that brief digital or traditional gameplay improved performance on tasks requiring quick responses but reduced performance on tasks demanding greater concentration and self-control.

Every 13 or 17 years, swarms of cicadas emerge from the ground, their black bodies, orange-tinged wings and ruby-red eyes enveloping trees and forests. It is a biological marvel unique in the insect world, and when it happens, it is impossible not to notice.

The Etruscan painted tombs in Tarquinia, Italy, date to the first millennium BCE and are known for their vivid scenes of music, feasting, processions and the afterlife. While these tombs have been extensively studied, archaeologists have typically looked at the paintings as images to decode rather than as parts of an experience that people moved through.

Researchers from Kanazawa University, the University of Tokyo and HORIBA, Ltd. have shown that the initial state of platinum-on-carbon (Pt/C) catalyst particles before they are mixed with an ionomer strongly influences how a polymer electrolyte fuel cell (PEFC) catalyst ink subsequently develops. The paper is published in the Chemical Engineering Journal.